The only way vertical missiles would out damage the large missile is if you're running them in a dual shoulder setup (assuming they all land 100% of the time), and even then, it's not a massive difference in damage. Vertical missiles aren't that difficult to dodge due to average tracking, and if someone who knows that their AC can't dodge them (slower ACs in general), they will buff them out. The large missile has the best tracking of any missile in the game, has double the explosion radius of all other KE missiles, so even if your opponent runs away and drags it into the terrain, there's a good chance it will still damage them and possibly their team members. Not to mention it's impossible to buff out and it will movement stagger any AC in the game, which can snowball the fight into your favor; do you know what happens to an AC that happens to get hit by a large missile (or two if they're running dual shoulder) along with Podenkas/Strekozas or Karasawas? http://i.imgur.com/EI5jMXy.png Chances are they're going to die unless they manage to get away from the sustained fire, which is kind of hard to do when you're getting movement staggered by the large missiles, and possibly other fire from other ACs. If you're wondering how that AC in the screenshot managed to live that long after being brought down below 10% AP, he was using Sawarabi LRJ legs and focused entirely on dodging for the rest of the time. Regarding the lack of ammo for the large missile: you might run out of ammo somewhat quickly, but being able to deal massive amounts of burst damage should not be underestimated, as it can shift the game in your team's favor. If anything, you can take advantage of an AC that is built around low ammo count weapons.